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Home > Prizes > Prize Recipients > Harris Wang

Harris Wang

2022 Vilcek Prize for Creative Promise in Biomedical Science

Portrait of Harris Wang

Location

New York, NY

Title

Associate Professor of Systems Biology, Columbia University;
Scientific Advisory Board Member, SNIPR Biome;
Scientific Advisory Board Member, Kingdom Supercultures

Area(s) of Research

Synthetic biology, microbiome engineering, systems biology

Education

Massachusetts Institute of Technology (BS);
Harvard University (PhD);
Harvard-MIT Health Sciences and Technology (HST), (joint PhD in Medical Engineering Medical Physics (MEMP)

Country of Birth

China

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Links to learn more about Harris Wang's work
  • Wang Lab

Tags
biology biomedical science biotechnology china CRISPR genetic engineering MAGE microbiome synthetic biology systems biology
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Portrait of Harris Wang

Harris Wang is a systems and synthetic biologist. An associate professor at Columbia University, he is widely regarded as a pioneer in the field of synthetic biology, a multidisciplinary field that encompasses biotechnology, genetic engineering, and systems biology to engineer organisms and systems for specific purposes.

Wang earned his bachelor’s in physics and applied mathematics at the Massachusetts Institute of Technology (MIT). Following his studies at MIT, Wang earned a Ph.D. in biophysics at Harvard University, and a joint Ph.D. in medical engineering and medical physics in the Harvard-MIT Program in Health Sciences and Technology.

Drawn to the field of synthetic biology, Wang joined the laboratory of George Church, where he pioneered Multiplex Automated Genome Engineering (MAGE), a platform for rapid genome editing and prototyping that enables scientists to generate potential genomic variants quickly and efficiently at scale. Wang then applied the platform to effectively reprogram the entire genome of E. coli. Hailed as a breakthrough, MAGE has played an important role in the expansion of synthetic biology.

Harris Wang sitting at a desk working on a computer.

At Columbia University, Wang’s research focuses on developing genomics and synthetic biology tools to understand the governing cellular and ecological principles that shape the structure and function of microbial communities. With his colleagues at Columbia, he developed CAMEOS – a platform to computationally design and experimentally test overlapping genes while controlling for adaptive mutations. Wang also devised an approach that enables scientists to genetically engineer the gut microbiome in mammals by engineering the mobilome known as MAGIC (Metagenomic Alteration of Gut microbiome by In situ Conjugation).

Born in Beijing, Wang lived in China until he was nine years old. His parents immigrated to the United States in 1989; his own immigration was delayed due to the Chinese government’s scrutiny of family immigration at the time. He was reunited with his parents three years after their departure, when he joined them in Salt Lake City, Utah. He credits the experience with teaching him patience and resilience—two attributes that have served him well in his career.

Harris Wang, arms folded, stands in a dark room in front of a microscope.

Awards and Accomplishments

  • Hirschl Trust Research Scientist Award (2019)
  • Schaefer Research Scholar, Columbia University (2018)
  • Harold & Golden Lamport Research Award in Basic Sciences, Columbia University (2017)
  • Investigator in Pathogenesis of Infectious Disease Award, Burroughs Wellcome Fund (2017)
  • Presidential Early Career Award for Scientists and Engineers (PECASE), National Science Foundation (2017)
  • ONR Director of Research Early Career Award, Office of Naval Research, Department of Defense (2017)
  • ONR Young Investigator of Award, Office of Naval Research, Department of Defense (2015)
  • Sloan Research Fellowship, Sloan Foundation (2015)
  • NSF CAREER Award, National Science Foundation (2014)
  • 30 Under 30 in Science, Forbes (2012)
  • NIH Director’s Early Independence Award, National Institutes of Health (2011)
  • Wyss Technology Development Fellowship, Wyss Institute, Harvard University (2011)
  • Collegiate Inventors Competition Grand Prize, National Inventors Hall of Fame (2009)
  • Certificate of Distinction in Teaching, Derek Bok Center, Harvard University (2009)
  • NSF Graduate Research Fellowship, National Science Foundation (2006)
  • National Defense Science and Engineering Graduate (NDSEG) Fellowship, Department of Defense (2006)
  • Exceptional Summer Student at NINDs, National Institutes of Health (2002)
  • National Merit Scholar (2001)

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Jury Members

2022 Vilcek Prize for Creative Promise in Biomedical Science

Heran Darwin

Professor, Department of Microbiology, New York University

Laurie Dempsey

Senior Editor, Nature Immunology, Nature Publishing Group

Yibin Kang

Warner-Lambert/Parke-Davis Professor of Molecular Biology, Princeton University

Harmit S. Malik

Principal Investigator, Fred Hutchinson Cancer Research Center

Luciano A. Marraffini

Kayden Family Professor, The Rockefeller University

Leslie B. Vosshall

Robin Chemers Neustein Professor of Neurogenetics and Behavior, The Rockefeller University

Jedd D. Wolchok

Lloyd J. Old/Virginia and Daniel K. Ludwig Chair in Clinical Investigation, Memorial Sloan Kettering Cancer Center
Tags
biology biomedical science biotechnology china CRISPR genetic engineering MAGE microbiome synthetic biology systems biology
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Related Prize Recipients

Biyu J. He

Biyu J. He receives the Vilcek Prize for Creative Promise in Biomedical Science for her leadership in the field of cognitive neuroscience, and for her groundbreaking discoveries on the biological bases of perceptual cognition and subjective experience.
Portrait of Biyu J. He.

Shixin Liu

Shixin Liu receives the Vilcek Prize for Creative Promise for applying cutting-edge biophysical tools to directly visualize, manipulate, and understand the physiological function of nanometer-scale biomolecular machines including DNA replication and transcription complexes at the single-molecule level.
Portrait of Shixin Liu.

Feng Zhang

Feng Zhang receives the Vilcek Prize for Creative Promise in Biomedical Science for using light to manipulate the activities of brain cells in living animals and for enabling rapid alterations to the genomes of living organisms.
Portrait of Feng Zhang

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