Skip to main content
Vilcek Foundation
  • About
    • About

      The Vilcek Foundation raises awareness of immigrant contributions in the United States and fosters appreciation of the arts and sciences.

    • Our Mission
    • Our Founders
    • Our Team
    • Press Center
    • Contact
  • Prizes
    • Prizes

      The Vilcek Foundation Prizes celebrate extraordinary achievements in the arts and sciences.

    • About the Prizes
    • Prize Recipients
    • Vilcek Prizes

      Awards immigrants with a legacy of major accomplishments.

    • Vilcek Prizes for Creative Promise

      Recognizes young immigrant professionals for outstanding achievements.

    • Vilcek Prize for Excellence

      Celebrating intellectual and cultural leaders in the United States.

    • Marica Vilcek Prize in Art History

      Honors art historians, curators, and fine arts professionals.

  • Art
  • Grants
    • Grants

      Grants awarded to 501(c)(3) cultural, educational, and philanthropic organizations in the United States.

    • Grants

      Learn more and apply for a grant.

    • Grants History

      Explore a list of past Vilcek Foundation grantees.

  • Events
  • News
Sign Up Search
Home > News > Ibrahim Cissé: The power of visibility

Ibrahim Cissé: The power of visibility

News | March 29, 2021
Tags
biological imaging biomedical science biophysics dna imaging microscopy MIT niger physics rna
Share this page
Share this page on X Share this page on Facebook Share this page on LinkedIn

Ibrahim Cissé with a big smile, wearing a red jacket, standing in front of the steps of an MIT building.

Growing up in Niamey, Niger, Ibrahim Cissé loved science. The youngest of five children, he was thrilled by the potential that experimentation provided for learning about and understanding the natural and physical world. With his family’s encouragement, he labeled a storage room in his family’s home the “Laboratoire Cissé.” It became the site of Ibrahim’s first experiments: deconstructing, learning about, and reconstructing his family’s appliances and devices.

One of the thrilling parts of working in a laboratory is waking up every day and not knowing what may be discovered by the day’s end, says Ibrahim. “Science is all about that,” he says. “If you limit your imagination, you are limiting questions you may ask that can lead you to incredible discoveries.”

Ibrahim now directs his own laboratory—the Cissé Lab—currently in the Department of Physics and the Department of Biology at Massachusetts Institute of Technology (MIT). The Cissé lab is also in the process of moving to the California Institute of Technology (Caltech), where Ibrahim is a professor of physics. “I feel like it’s still playtime. It’s still fun, and it’s still curiosity-driven,” he says. Ibrahim receives a Vilcek Prize for Creative Promise in Biomedical Science for using super-resolution biological imaging to directly visualize the dynamic nature of gene expression in living cells.

Ibrahim writes in a notebook at a table on a rooftop deck.

The Cissé Lab focuses on the use of microscopic techniques and technologies that enable scientists to observe the behavior of individual biomolecules in living cells. Using single-molecule based, live cell super-resolution microscopy (so-called PALM and STORM microscopy), Ibrahim has been able to observe the physical properties and behaviors of RNA polymerase enzymes as they decode DNA into RNA. These observations allow researchers to better understand how concepts from physics—including condensed matter physics, fluid dynamics, and mechanics—can be applied to understand biological processes. The techniques that Ibrahim’s work has pioneered also have the potential to help scientists to better understand the way protein aggregates form in neurodegenerative diseases like Parkinson’s, ALS, and Alzheimer’s.

Ibrahim Cissé wearing a red jacket sits smiling on the steps of an MIT building.

“Physics is a really solid framework on which to understand nature from a very fundamental and mathematical standpoint,” says Ibrahim. “[It enables us] to take this complex problem, and break it down and frame it in a constructive manner.”

The importance of open-mindedness and flexibility in problem solving is of particular importance to Ibrahim. While participating in a summer internship at Princeton, Ibrahim was presented with a question of how the geometry of an object could be used to understand relative packing density and points of contact when packed at random in a container. Using M&M’s candies and paint, Ibrahim designed a creative experiment that helped him and his team make a discovery. They published their findings in Science magazine while Ibrahim was still an undergraduate at North Carolina Central University.

A researcher works with green and blue lasers in the Cissé Lab at MIT.

Ibrahim’s experiences at North Carolina Central University have profoundly shaped his approach to science and mentorship. “Having trained at a historically Black college was just an incredible way of learning to see and think about race, and not just in America but also in Africa,” he says. “It gave me the knowledge and that empowerment that, no matter what adversity I was going to face, it is important to move forward in a way that will empower others and create opportunity for others.”

“It’s important for students—especially those who come from underprivileged backgrounds—to realize that the best thing they have, beside talent and hard work, is the creativity and the level of enthusiasm they can bring to the table,” says Ibrahim. “Everything else can be learned.”

Tags
biological imaging biomedical science biophysics dna imaging microscopy MIT niger physics rna
Share this page
Share this page on X Share this page on Facebook Share this page on LinkedIn

Related News

September 29, 2021

Biophysicist Ibrahim Cissé receives prestigious MacArthur Fellowship

Vilcek Foundation Prizewinner Ibrahim Cissé (b. Republic of Niger) is the recipient of a 2021 MacArthur Fellowship from the MacArthur Foundation.
Ibrahim Cissé wearing a black blazer and shirt, smiles standing on a rooftop.
March 13, 2023

Shixin Liu: “Seeing is believing”

Born in Anhui province, China, molecular biologist Shixin Liu is passionate about understanding and visualizing the molecular interactions that drive functions like gene expression.
Shixin Liu wearing a black sweater framed by the tree trunks behind him.
February 22, 2021

Ruth Lehmann: “There’s always another question… there’s always more to find out”

Molecular and cellular biologist Ruth Lehmann receives the Vilcek Prize in Biomedical Science for her research and leadership in the field.
A portrait of Ruth Lehmann in a black blazer as she stands on a bridge over the Charles River.

You may also be interested in

Ibrahim Cissé

Ibrahim Cissé receives the Vilcek Prize for Creative Promise in Biomedical Science for using super-resolution biological imaging to directly visualize the dynamic nature of gene expression in living cells.
Portrait of Ibrahim Cissé

Shixin Liu

Shixin Liu receives the Vilcek Prize for Creative Promise for applying cutting-edge biophysical tools to directly visualize, manipulate, and understand the physiological function of nanometer-scale biomolecular machines including DNA replication and transcription complexes at the single-molecule level.
Portrait of Shixin Liu.

Hashim Al-Hashimi

Hashim Al-Hashimi receives the Vilcek Prize for Creative Promise in Biomedical Science for using biophysical and computational methods to probe the dynamic properties of life-sustaining biomolecules such as DNA, RNA, and the proteins that interact with them, paving the way toward targeted drug discovery.
Hashim Al-Hashimi

Join our mailing list

Sign Up
Vilcek Foundation
21 East 70th Street
New York, New York 10021

Phone: 212.472.2500

Email: info@vilcek.org

  • About
    • Our Mission
    • Our Founders
    • Our Team
    • Press Center
    • Contact
  • Prizes
    • Prize Recipients
    • Vilcek Prizes
    • Vilcek Prizes for Creative Promise
    • Vilcek Prize for Excellence
    • Marica Vilcek Prize in Art History
  • Art
  • Grants
    • Grants History
  • Events
  • News
  • Careers
Connect with us
  • Connect with the Vilcek Foundation on Facebook
  • Connect with the Vilcek Foundation on Instagram
  • Connect with the Vilcek Foundation on X
  • Connect with the Vilcek Foundation on LinkedIn
  • Connect with the Vilcek Foundation on Youtube
  • Connect with the Vilcek Foundation on Vimeo
  • Privacy Policy
  • Accessibility Statement
© 2025   Vilcek Foundation
We use cookies to ensure that we give you the best experience on our website. If you continue to use this site we will assume that you are happy with it.Ok