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Home > Prizes > Prize Recipients > Konrad Hochedlinger

Konrad Hochedlinger

2012 Vilcek Prize for Creative Promise Honoree in Biomedical Science

Location

Cambridge, MA

Title

Associate professor, Department of Stem Cell and Regenerative Biology, Stem Cell Institute, Harvard University; Professor, Cold Spring Harbor Laboratory

Area(s) of Research

Cell reprogramming; treatment of degenerative diseases

Education

Research Institute of Molecular Pathology (PhD, mammalian development); Research Institute of Molecular Pathology, Vienna; Whitehead Institute/MIT (visiting graduate student)

Country of Birth

Austria

Tags
biomedical science
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A black and white photo of Konrad Hochedlinger wearing a lab coat in front of equipment.
Photo courtesy of Mass General

Austrian-born Konrad Hochedlinger can trace a direct line from the seminal cloning experiments of the ‘60s to his current position as associate professor at Harvard’s Stem Cell Institute, Department of Stem Cell and Regenerative Biology. Those early experiments, conducted by John Gurdon, led to his decision to attend the Research Institute of Molecular Pathology, in Vienna, for graduate work. While there, he attended a lecture given by Rudolf Jaenisch, who proposed to use animal cloning. Fascinated by this concept, he applied, successfully, to join Jaenisch’s lab as a visiting graduate student at the Whitehead Institute/MIT. In his six years there, Hochedlinger says, he “learned how to think scientifically and ask fundamental questions in stem cell biology.” He also succeeded in generating cloned mice, from fully specialized immune cells.

At his independent lab today, Hochedlinger works to understand the “elusive mechanisms of cellular reprogramming.” His ultimate goal is to utilize this information for the generation of patient-specific stem cells in drug discovery efforts and for the treatment of degenerative diseases. In addition to his research activities, he enjoys teaching courses at both Harvard and the Cold Spring Harbor Laboratory. He does not shy away from addressing the often controversial scientific, ethical, and legal issues surrounding stem cell research, and welcomes the opportunity to speak with lay audiences on these topics. Hochedlinger earned his PhD in mammalian development from the Research Institute of Molecular Pathology.

Jury Members

2012 Vilcek Prize for Creative Promise Honoree in Biomedical Science

Heran Darwin

Associate Professor of Microbiology, New York University School of Medicine

Laurie Dempsey

Senior Editor, Nature Immunology

Peter Palese

Professor and Chair, Microbiology, Mount Sinai School of Medicine

Jan Vilcek

Professor of Microbiology, New York University School of Medicine

Leslie Vosshall

Chemers Family Associate Professor, The Rockefeller University

Nicholas Wade

Science Department, The New York Times

Jedd Wolchok

Director of Immunotherapy, Memorial Sloan Kettering Cancer Center
Tags
biomedical science
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Related Prize Recipients

Angelika Amon

Angelika Amon (1967-2020) receives the Vilcek Prize in Biomedical Science for groundbreaking research on the molecular signals that regulate cell growth and division, and how errors in these processes contribute to birth defects and cancer.
Portrait of Angelika Amon

Andreas Hochwagen

Andreas Hochwagen is an honoree for the Vilcek Prize for Creative Promise in Biomedical Science.
A photo of Andreas Hochwagen in his lab.

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Songhai Shi is an honoree for the Vilcek Prize for Creative Promise in Biomedical Science.
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